Abstract. Advanced solid breeding blanket design in the DEMO reactor requires the tritium breeder and neutron multiplier that can withstand the high temperature and high dose of neutron irradiation. Therefore, the development of such advanced blanket materials is indispensable. In this paper, the cooperation activities among JAERI, universities and industries in Japan on the development of these advanced materials are reported. Advanced tritium breeding material to prevent the grain growth in high temperature had to be developed because the tritium release behavior degraded by the grain growth. As one of such materials, TiO2-doped Li2TiO3 has been studied, and TiO2-doped Li2TiO3 pebbles was successfully fabricated. For the advanced neutron multiplier, the beryllium intermetallic compounds that have high melting point and good chemical stability have been studied. Some characterization of Be12Ti was studied. The pebble fabrication study for Be12Ti was also performed and Be12Ti pebbles were successfully fabricated. From these activities, the bright prospect to realize the DEMO blanket by the application of TiO2-doped Li2TiO3 and beryllium intermetallic compounds was obtained.