The growing operational demands in nuclear fuel, such as longer fuel cycles, higher burnups and use of transient regimes, call for more robust fuel designs and more radiation resistant materials. Implementation of new materials and fuel designs that are able to meet these more challenging conditions requires adequate operational feedback and practical verification of models for prediction of fuel behaviour. This CD-ROM publication presents the proceedings of a technical meeting jointly held by the IAEA and the HOTLAB association of hot laboratories with the aim of providing an overview of the current status, problems and perspectives of post-irradiation examination. The publication consists of the presentations, session summaries and conclusions of the meeting.