Effective management of the ageing of structures, systems and components has become an important issue for IAEA Member States, since out of the total number of nuclear power plants (NPPs) operating in the world, many have been in operation for more than 30 years and at least half for more than 20 years. Proactive management of ageing is a key element in ensuring the safe and reliable operation of NPPs. This publication supplements the Safety Guide, Ageing Management for Nuclear Power Plants, and provides practical examples of how to manage ageing degradation effectively. It provides guidance and good practices for maintaining and enhancing the safety and performance of NPPs by facilitating the implementation of proactive ageing management throughout their lifetime.