This status report briefly describes the recent nuclear seawater desalination related developments in IAEA Member States as well as relevant IAEA activities. It covers salient aspects of the new generation reactors and some innovative reactors being considered for desalination applications, recent advances in commonly employed desalination processes and their coupling to nuclear reactors. A summary of the techno-economic feasibility studies carried out in interested Member States is presented. The socioeconomic and environmental benefits of nuclear power driven desalination plants are discussed.