This report presents guidelines to the designers of water cooled power reactors which will minimize the impact of IAEA safeguards on plant operations and ensure efficient and effective acquisition of safeguards data to the mutual benefit of the Member State, the plant operator and the IAEA. These guidelines incorporate the IAEA's experience in establishing and carrying out safeguards at currently operating nuclear power plants, the ongoing development of safeguards techniques and the feedback of experience from plant operators and designers on the impact of IAEA safeguards on plant operation. Contents: 1. Introduction; 2. The IAEA's safeguards function for current and future nuclear power plants; 3. Summary of the political and legal foundations of the IAEA's safeguards system; 4. The technical objective of safeguards and the supply and use of required design information; 5. Safeguards approaches for nuclear power plants; 6. Design implications of experience in safeguarding nuclear power plants; 7. Guidelines for design provisions for future water cooled reactors to facilitate the implementation of safeguards; Appendix I: Summary of information requested in the IAEA's Design Information Questionnaire; Appendix II: IAEA safegu