The idea of using tracers (chemical tracers, dyes, etc.) in the investigation of complex physical phenomena has always attracted the attention of scientists and engineers. When radioactive isotopes became available it was immediately recognized that they offered an almost ideal solution to tracer selection. Extensive experience has been gathered all over the world in the application of radioactive tracers in industry. This guide is devoted to reviewing the present status of the tracer method as such and to its applications to those branches of industry which have derived large benefits from the use of this technology. Contents: Chapter 1. Introduction; Chapter 2. The concept of tracers; Chapter 3. General tracer technology; Chapter 4. Tracer methodology; Chapter 5. General applications; Chapter 6. Case studies; Chapter 7. Current trends in development and applications; Annexes I–VI.